Clinical Applications

• Supports Healthy Blood Circulation
• Promotes Bone Health and Proper Calcium Storage
• Maintains Healthy Cardiometabolic Function and Supports Blood Sugar Balance Already Within Normal Levels
• Boosts Immune Function

Overview

While vitamin D has long been known to assist calcium absorption, it is vitamin K, through its carboxylation of osteocalcin, which guides this calcium to bones and prevents their absorption into organs, joint spaces and arteries. Vitamin K occurs in 2 main forms: K1 (phylloquinone), derived from foods such as green leafy vegetables and K2 (menaquinone), which is a group of related compounds differentiated by their side chains. Numerous studies have shown that vitamin K2 is the more bioavailable form of the nutrient7, and more powerfully influences bone building than K1. In addition, though both reach the liver, most of the K1 is used for purposes of coagulation, with little left over to support the body’s needs elsewhere.8 The profoundly different degrees of bioavailability between K1 and K2 is due to their differences in structure; only 10-20% of vitamin K1 that is absorbed from food even reaches the circulation, while the long side-chain of vitamin K2 allows it to bind with fat particles in circulation and facilitate its arrival at soft tissue, bones and arteries. There are two forms of vitamin K2 commonly used in supplements: MK-4 and MK-7. The MK-7 form has been shown to have six times the activity of MK-4 in the blood. MK-7 has also been found to remain in the blood approximately nine times as long as the MK-4 (eight hours versus 72 hours), making it the optimal form of K2.9

The addition of MenaQ7® PRO to this formula is backed by extensive research. Dr. Leon Schurgers, world-renowned expert in vitamin K2 as MK-7 research for cardiovascular and bone health, and his team of research scientists have conducted over 15 clinical trials on MenaQ7® PRO through the University of Maastricht.

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